Clinical research & methodology
Research that survives peer review.
Study design, advanced statistical analysis, systematic reviews and manuscript support — delivered by medical doctors who publish, with every result independently verified and reproducible from raw data to final table.
No obligation · Sun–Thu, 09:00–18:00 GMT+2 · We work worldwide
Three factors that make a research institution reliable
- 01 A research-active medical team Every member: 50+ publications, h-index ≥ 5. Researchers, not only clinicians.
- 02 A proven track record at scale 1,000+ researchers supported across 5,000+ projects, spanning every specialty and study design.
- 03 Structured quality control Data checks, appropriate methodology, independent review and reproducible practice before anything is delivered.
Reliability isn't a claim. It's a process you can ask to see.
Every ClinStat team member is a practising medical doctor with an active research record — a minimum of 50 scientific publications and an h-index of 5 or higher.
What we do
Support at every stage — not just the analysis at the end.
Most of the problems we are asked to rescue at the analysis stage were created at the design stage. We work across the whole arc, from research question to reviewer response.
Biostatistics & data analysis
Descriptive statistics through to advanced modelling — with assumptions tested, methods justified, and every number reproducible.
Explore this serviceStudy design & protocol development
The cheapest place to fix a study is before the first patient is enrolled. Design, sample size and analysis plan, agreed in advance.
Explore this serviceSystematic review & meta-analysis
Protocol, search, screening, extraction, risk of bias, pooling, heterogeneity and certainty — done to a standard that survives editorial screening.
Explore this serviceData management & validation
Before any analysis: duplicates, impossible values, inconsistent coding, eligibility errors and missingness patterns found and resolved — with a full audit trail.
Explore this serviceManuscript & publication support
Writing, scientific editing, reporting-guideline compliance, journal selection, submission and point-by-point reviewer responses.
Explore this serviceResearch mentorship
Structured, project-based training that ends with you running your own research — not with you needing us again.
Explore this serviceThe standard
What actually makes a research finding “reliable”?
Not a vibe — a checklist. Eight checks run on every project, before the result is allowed to become a conclusion.
- High-quality, validated data
- A design and sample size that can answer the question
- A statistical analysis matched to the design
- Model assumptions formally tested
- Sensitivity and robustness analyses
- Missing data addressed, not deleted
- Independent verification by a second statistician
- Full reproducibility from raw data to final table
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A highly qualified, research-active medical team
Our team is made up of medical doctors actively involved in scientific research — every member has at least 50 scientific publications and an h-index of 5 or higher. That means sustained, current experience in research methodology, scientific writing, peer review and academic publishing, not clinical expertise alone.
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Extensive experience and a proven track record
More than 1,000 researchers and clients supported across over 5,000 research projects, spanning different specialties, study designs and stages of the research process. A portfolio that size is what produces judgement about complex research questions, statistical analyses, systematic reviews, manuscripts and publication problems.
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Real quality-control and research infrastructure
Reliable research takes more than individual expertise. We run a structured workflow with data-quality checks, appropriate statistical methodology, independent review of every analysis, reproducible research practices and scientific quality assurance before anything is delivered.
Methodological depth
If your project touches any of these, it is exactly our specialty — not a side skill.
18 advanced method families our team works with routinely. Each one is the difference between an analysis that looks correct and one that is.
Propensity scores, IPTW & doubly robust estimation
Comparing groups that were never randomised, without pretending confounding away.
Longitudinal & repeated-measures modelling
Measurements taken from the same patient are not independent — and analysing them as if they were inflates significance.
Survival & competing-risk analysis
Time-to-event data is not about death. It is about when anything happens — and what else could have happened first.
Missing-data methodology
Deleting every patient with a gap is a decision about your results, not a neutral default.
Advanced, network, IPD & diagnostic meta-analysis
Pooling is the easy part. Heterogeneity, transitivity and inconsistency are where reviews are won or lost.
Prediction model development, validation & machine learning
A model that discriminates well and calibrates badly will still give the wrong answer to a real patient.
Multiplicity & false discovery control
Test twenty outcomes at the 5% level and one will look significant by construction.
Sensitivity & robustness analysis
A finding that only exists under one set of analytical choices is not a finding.
Mediation & moderation analysis
Not just whether an exposure works — through what, and for whom.
Also in routine use
How a project runs
Every project we take on follows the same path.
A process built for accuracy. Results built for impact.
- UnderstandA free 15-minute call to establish the research question, what data exist, and what the deadline really is.
- PlanDesign review or a written statistical analysis plan tied to the question — agreed before any modelling begins.
- ValidateStructured data validation: ranges, logic, duplicates, coding harmonisation, eligibility and missingness, with an audit trail.
- AnalyseThe analysis the question requires, with assumptions tested and sensitivity analyses run, in reproducible code.
- VerifyA second statistician independently reproduces every primary result from the cleaned dataset.
- DeliverPublication-ready tables, figures, methods and results text — plus the scripts, so every number is traceable.
Evidence
What the work actually changes.
Three documented projects — a dataset that was not what it appeared to be, a partnership at scale, and a manuscript everyone had given up on.
From a difficult raw dataset to a publication-ready clinical study
A 1,800-patient multicentre retrospective dataset, two weeks to a submission deadline, and a preliminary analysis that turned out to be wrong.
Research at scale: ~100 papers a quarter, 80% published
Supporting an academic institution across design, analysis, writing and journal selection — at a volume that only works with a structured workflow.
Rejected by more than ten journals — accepted by the next one
Repeated rejection is usually a diagnosis problem. This manuscript had four separate ones — and a journal strategy that was never going to work.
Free resource
Before you submit — check it against this.
Most desk rejections come down to the same avoidable gaps. This is the 12-point checklist our team runs internally before any manuscript goes out. It takes about ten minutes, and it is completely free.
The three that end most papers early
All three are avoidable with one structured review before submission — not after rejection.
Trusted by researchers worldwide
A few words from those we work with.
“Professional, detail-oriented, scientifically rigorous and true to success at every step of our research.”
“Exceptional expertise and support throughout the entire process.”
“They turned a complex problem into clear answers we could actually use.”
“They clarified everything. The results speak for themselves.”
“Our go-to team for biostatistics and study design.”
Let’s make your next result defensible.
Book a free 15-minute consultation. Tell us the research question, the data you have, and the deadline — we will tell you honestly what is achievable.
Or call +20 100 163 8864 · Sunday–Thursday, 09:00–18:00 (GMT+2, Cairo)